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2019新型冠状病毒研究论文
文章来源:    发布时间:2020-05-15    【字号:

A human neutralizing antibody targets the receptor binding site of SARS-CoV-2 

Shi, R., Shan, C., Duan, X. et al. 

Nature 

Published: 26 May 2020 

DOI: https://doi.org/10.1038/s41586-020-2381-y 

  

Structural basis for RNA replication by the SARS-CoV-2 polymerase 

Wang Q, Wu J, Wang H, et al. 

Cell 

Published: 22 May 2020 

DOI:https://doi.org/10.1016/j.cell.2020.05.034 

 

Pathogenesis of SARS-CoV-2 in transgenic mice expressing human angiotensin-converting enzyme 2 

Jiang R, Liu M, Chen Y, et al. 

Cell 

Published: 21 May 2020 

DOI: https://doi.org/10.1016/j.cell.2020.05.027 

 

Gemcitabine, lycorine and oxysophoridine inhibit novel coronavirus (SARS-CoV-2) in cell culture 

Zhang Y, Zhang Q, Li X, et al. 

Emerging Microbes & Infections 

Published: 20 May 2020 

DOI: https://doi.org/10.1080/22221751.2020.1772676 

 

Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies 

Yi C, Sun X, Ye J, et al. 

Cell Mol Immunol. 

Published: 15 May 2020 

DOI: https://doi.org/10.1038/s41423-020-0458-z 

  

Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur 

Jin Z, Zhao Y, Sun Y, et al. 

Nat Struct Mol Biol. 

Published: 07 May 2020 

DOI: https://doi.org/10.1038/s41594-020-0440-6 

 

The anti-influenza virus drug, arbidol is an efficient inhibitor of SARS-CoV-2 in vitro 

Wang, X., Cao, R., Zhang, H. et al. 

Cell Discov 6, 28 (2020) 

Published: 02 May 2020 

DOI: https://doi.org/10.1038/s41421-020-0169-8 

 

The Importance Of Naturally Attenuated Sars-Cov-2 In The Fight Against Covid-19 

Armengaud J, Delaunay-Moisan A, Thuret JY, et al. 

Environ Microbiol. 

Published: 28 April 2020 

DOI: https://doi.org/10.1111/1462-2920.15039 

 

Plasma Metabolomic and Lipidomic Alterations Associated with COVID-19 

Wu D, Shu T, Yang X, et al. 

National Science Review 

Published: 28 April 2020 

DOI: https://doi.org/10.1093/nsr/nwaa086 

 

SARS-CoV-2 Infection in Children 

Lu X, Zhang L, Du H, et al. 

N Engl J Med., 382(17):1663–1665 

Published: 23 April 2020 

DOI: https://doi.org/10.1056/NEJMc2005073 

  

Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 

Dai W, Zhang B, Jiang X, et al. 

Science 

Published: 22 April 2020 

DOI: https://doi.org/10.1126/science.abb4489 

  

Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients 

Chen X, Zhao B, Qu Y, et al. 

Clin Infect Dis. 

Published: 17 April 2020 

DOI: https://doi.org/10.1093/cid/ciaa449 

  

SARS-CoV-2-encoded nucleocapsid protein acts as a viral suppressor of RNA interference in cells 

Mu J, Xu J, Zhang L, et al. 

Sci China Life Sci. 

Published: 10 April 2020 

DOI: https://doi.org/10.1007/s11427-020-1692-1 

  

Structure of M pro From COVID-19 Virus and Discovery of Its Inhibitors 

Jin Z, Du X, Xu Y, et al.  

Nature 

Published: 9 April 2020 

DOI: https://doi.org/10.1038/s41586-020-2223-y 

  

Rapid and visual detection of 2019 novel coronavirus (SARS-CoV-2) by a reverse transcription loop-mediated isothermal amplification assay 

Yan C, Cui J, Huang L, et al. 

Clin Microbiol Infect. 

Published: 7 April 2020 

DOI: https://doi.org/10.1016/j.cmi.2020.04.001 

  

Effectiveness of convalescent plasma therapy in severe COVID-19 patients 

Duan K, Liu B, Li C, et al. 

PNAS 

Published: 6 April 2020 

DOI: https://doi.org/10.1073/pnas.2004168117 

  

Inhibition of SARS-CoV-2 (Previously 2019-nCoV) Infection by a Highly Potent Pan-Coronavirus Fusion Inhibitor Targeting Its Spike Protein That Harbors a High Capacity to Mediate Membrane Fusion 

Xia S, Liu M, Wang C, et al. 

Cell Research, 30(4):343-355 

Published: 30 March 2020 

DOI: https://doi.org/10.1038/s41422-020-0305-x 

  

Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro  

Liu J, Cao R, Xu M, et al.   

Cell Discovery volume 6, Article number: 16 (2020) 

Published: 18 March 2020 

DOI: https://doi.org/10.1038/s41421-020-0156-0 

  

A distinct name is needed for the new coronavirus 

Jiang S, Shi Z, Shu Y, et al. 

Lancet, 395(10228):949 

Published: 19 Feburary 2020 

DOI: https://doi.org/10.1016/S0140-6736(20)30419-0 

  

Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes  

Zhang W, Du RH, Li B, et al. 

Emerg Microbes Infect., 9(1):386-389 

Published: 17 Feburary 2020 

DOI: https://doi.org/10.1080/22221751.2020.1729071 

  

Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody 

Tian X, Li C, Huang A, et al. 

Emerg Microbes Infect., 9(1):382–385 

Published: 17 Feburary 2020 

DOI: https://doi.org/10.1080/22221751.2020.1729069 

  

The First Disease X is Caused by a Highly Transmissible Acute Respiratory Syndrome Coronavirus  

Jiang S, Shi ZL 

Virol Sin. 

Published: 14 Feburary 2020 

DOI: https://doi.org/10.1007/s12250-020-00206-5 

  

Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein 

Xia S, Zhu Y, Liu M, et al. 

Cell Mol Immunol. 

Published: 11 Feburary 2020 

DOI: https://doi.org/10.1038/s41423-020-0374-2 

  

Clinical Features and Treatment of 2019-nCov Pneumonia Patients in Wuhan: Report of A Couple Cases   

Zhang Z, Li X, Zhang W, Shi ZL, Zheng Z, Wang T. 

Virol Sin. 

Published: 7 Feburary 2020 

DOI: https://doi.org/10.1007/s12250-020-00203-8 

  

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro  

Wang M, Cao R, Zhang L, et al. 

Cell Research volume 30, pages 269–271 

Published: 04 February 2020 

DOI: https://doi.org/10.1038/s41422-020-0282-0 

  

A pneumonia outbreak associated with a new coronavirus of probable bat origin 

Zhou P, Yang XL, Wang XG, et al. 

Nature volume 579, pages 270–273 

Published: 03 February 2020 

DOI: https://doi.org/10.1038/s41586-020-2012-7 

  

An emerging coronavirus causing pneumonia outbreak in Wuhan, China: calling for developing therapeutic and prophylactic strategies 

Jiang S, Du L, Shi Z. 

Emerg Microbes Infect., 9(1):275-277 

Published: 31 January 2020 

DOI: https://doi.org/10.1080/22221751.2020.1723441